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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21334 | Bucillamine | DE-019,Thiobutarit,Tiobutarit,SA96,DE 019,DE019 | VEGFR , Antioxidant |
Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF. Bucillamine is an orally active sulfhydryl donor and antioxidant with antirheumatic and... | |||
T23666 | AGN-199659 | AGN 199659,AGN199659 | |
AGN-199659 is a novel tyrosine kinase inhibitor. It also blocks choroidal neovascularization. | |||
T69479 | CGC 11093 | ||
CGC 11093 is a polyamine analog; inhibits growth of human prostate tumor xenografts in nude mice. It may prove useful in promoting regression of choroidal neovascularization. | |||
T36718 | Tie2 Inhibitor 7 | ||
Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 μM.. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC50 value of 0.3 μM. This compound c... | |||
T35494 | (±)11(12)-EET | ||
(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.[1][2][3[]A higher proportion of 11(R),12(S)-EET is produced by the CYP450 isoforms C... |